What is Viagra? Know the story of the medicine that became the most popular medicine in the world by mistake

Viagra, commonly known as ‘small blue tablet’, is a highly popular drug for the treatment of erectile dysfunction (problem of penis failure) worldwide. Today millions of men use this medicine, but it was discovered by a chance. In fact, it was initially being built to treat heart disease (angina), but during the trial it was revealed that no one expected.

How was Viagra discovered?

In the early 1990s, the drug manufacturer was making a new drug for Phizer’s scientist Angina (pain caused by blood flow deficiency). During this research, he worked on a compound called Sildenafil.

Sildenafil blocks an enzyme called PDE5, which narrows the blood arteries in the body. Its effect was that blood vessels started spreading and the men participating in the trial unexpectedly came to erection.

Initially scientists did not imagine it

Sir Simon Campbell, a scientist working on medicine, said in an interview, “Our team was young and we were not at all concerned about the problem like erectile dysfunction. We did not know that there was any need in this direction.”

When trial volunteers refused to return the medicine

When the clinical trial ended, some volunteers refused to return their medicines. He expressed his desire to continue taking it. This reaction forced the research team to understand that this drug is more effective for erectile dysfunction than heart disease. After this it was brought to the market under the brand name Viagra.

How does Viagra work?

Viagra i.e. Sildenafil, a compound in the smooth muscle cells of the blood vessels in the men’s penis, prevents the breakdown of the cycle GMP. This increases blood flow during sexual stimulation and keeps stress. The same cycle GP does not form sufficient in men suffering from erectile dysfunction.

Viagra proved to be superhit

In the year 1998, Viagra was approved by the FDA and within a week, more than 1 million people were prescribed. Today, according to Fizer, more than 6.2 million men worldwide use it.

Later clinical trials also revealed that Sildenafil can also be used in severe heart conditions such as pulmonary arterial hypertension, which matches its early purpose.

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